The Abandoned Radical Hysterectomy for Cervical Cancer: Clinical Predictors and Outcomes
Identifieur interne : 005586 ( Main/Exploration ); précédent : 005585; suivant : 005587The Abandoned Radical Hysterectomy for Cervical Cancer: Clinical Predictors and Outcomes
Auteurs : Heidi J. Gray [États-Unis] ; Erin Seifert [États-Unis] ; Victor G. Sal Y Rosas [États-Unis] ; Katrina F. Nicandri [États-Unis] ; Wui-Jin Koh [États-Unis] ; Barbara A. Goff [États-Unis]Source :
- Obstetrics and Gynecology International [ 1687-9589 ] ; 2010.
Abstract
Url:
DOI: 10.1155/2010/743794
PubMed: 20454444
PubMed Central: 2861195
Affiliations:
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Gray</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195</wicri:regionArea><wicri:noRegion>WA 98195</wicri:noRegion></affiliation></author><author><name sortKey="Seifert, Erin" sort="Seifert, Erin" uniqKey="Seifert E" first="Erin" last="Seifert">Erin Seifert</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195</wicri:regionArea><wicri:noRegion>WA 98195</wicri:noRegion></affiliation></author><author><name sortKey="Sal Y Rosas, Victor G" sort="Sal Y Rosas, Victor G" uniqKey="Sal Y Rosas V" first="Victor G." last="Sal Y Rosas">Victor G. 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Nicandri</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Obstetrics and Gynecology, University of Rochester School of Medicine, Rochester, NY 14642, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Rochester School of Medicine, Rochester, NY 14642</wicri:regionArea><wicri:noRegion>NY 14642</wicri:noRegion></affiliation></author><author><name sortKey="Koh, Wui Jin" sort="Koh, Wui Jin" uniqKey="Koh W" first="Wui-Jin" last="Koh">Wui-Jin Koh</name><affiliation wicri:level="4"><nlm:aff id="I4">Department of Radiation Oncology, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, University of Washington, Seattle, WA 98195</wicri:regionArea><orgName type="university">Université de Washington</orgName><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Goff, Barbara A" sort="Goff, Barbara A" uniqKey="Goff B" first="Barbara A." last="Goff">Barbara A. Goff</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195</wicri:regionArea><wicri:noRegion>WA 98195</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">20454444</idno><idno type="pmc">2861195</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861195</idno><idno type="RBID">PMC:2861195</idno><idno type="doi">10.1155/2010/743794</idno><date when="2010">2010</date><idno type="wicri:Area/Pmc/Corpus">002689</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002689</idno><idno type="wicri:Area/Pmc/Curation">002688</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002688</idno><idno type="wicri:Area/Pmc/Checkpoint">003197</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">003197</idno><idno type="wicri:Area/Ncbi/Merge">003B00</idno><idno type="wicri:Area/Ncbi/Curation">003B00</idno><idno type="wicri:Area/Ncbi/Checkpoint">003B00</idno><idno type="wicri:doubleKey">1687-9589:2010:Gray H:the:abandoned:radical</idno><idno type="wicri:Area/Main/Merge">005634</idno><idno type="wicri:Area/Main/Curation">005586</idno><idno type="wicri:Area/Main/Exploration">005586</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The Abandoned Radical Hysterectomy for Cervical Cancer: Clinical Predictors and Outcomes</title><author><name sortKey="Gray, Heidi J" sort="Gray, Heidi J" uniqKey="Gray H" first="Heidi J." last="Gray">Heidi J. Gray</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195</wicri:regionArea><wicri:noRegion>WA 98195</wicri:noRegion></affiliation></author><author><name sortKey="Seifert, Erin" sort="Seifert, Erin" uniqKey="Seifert E" first="Erin" last="Seifert">Erin Seifert</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195</wicri:regionArea><wicri:noRegion>WA 98195</wicri:noRegion></affiliation></author><author><name sortKey="Sal Y Rosas, Victor G" sort="Sal Y Rosas, Victor G" uniqKey="Sal Y Rosas V" first="Victor G." last="Sal Y Rosas">Victor G. Sal Y Rosas</name><affiliation wicri:level="4"><nlm:aff id="I2">Department of Biostatistics, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Washington, Seattle, WA 98195</wicri:regionArea><orgName type="university">Université de Washington</orgName><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Nicandri, Katrina F" sort="Nicandri, Katrina F" uniqKey="Nicandri K" first="Katrina F." last="Nicandri">Katrina F. Nicandri</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Obstetrics and Gynecology, University of Rochester School of Medicine, Rochester, NY 14642, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Rochester School of Medicine, Rochester, NY 14642</wicri:regionArea><wicri:noRegion>NY 14642</wicri:noRegion></affiliation></author><author><name sortKey="Koh, Wui Jin" sort="Koh, Wui Jin" uniqKey="Koh W" first="Wui-Jin" last="Koh">Wui-Jin Koh</name><affiliation wicri:level="4"><nlm:aff id="I4">Department of Radiation Oncology, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, University of Washington, Seattle, WA 98195</wicri:regionArea><orgName type="university">Université de Washington</orgName><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Goff, Barbara A" sort="Goff, Barbara A" uniqKey="Goff B" first="Barbara A." last="Goff">Barbara A. Goff</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195</wicri:regionArea><wicri:noRegion>WA 98195</wicri:noRegion></affiliation></author></analytic><series><title level="j">Obstetrics and Gynecology International</title><idno type="ISSN">1687-9589</idno><idno type="eISSN">1687-9597</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><italic>Objective</italic>. Cervical cancer patients who had an abandoned radical hysterectomy were evaluated for preoperative clinical predictors, complication rates, and outcomes.
<italic>Study Design</italic>. IRB approval was obtained for this retrospective analysis and chart review was performed.
<italic>Results</italic>. From 268 women with early-stage (IA2 to IIA) cervical cancer, 19 (7%) had an abandoned hysterectomy for finding grossly positive lymph nodes (84%) or pelvic spread of tumor (16%). No clinical characteristics clearly identified women preoperatively at risk of having an abandoned hysterectomy. In the abandoned group, 26% suffered major morbidities, compared to 34% in the completed group (OR 0.69, [CI 0.16–2.57], <italic>P</italic> = .789). Thirty-seven percent recurred in the abandoned group, compared to 18% in the completed group (<italic>P</italic> = .168). Overall survival in the abandoned group was 73% versus 80% in the completed group (<italic>P</italic> = .772).
<italic>Conclusion</italic>. The practice of abandoning a planned radical hysterectomy for unexpected metastatic disease may not worsen the outcome.
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Gray</name></noRegion><name sortKey="Goff, Barbara A" sort="Goff, Barbara A" uniqKey="Goff B" first="Barbara A." last="Goff">Barbara A. Goff</name><name sortKey="Koh, Wui Jin" sort="Koh, Wui Jin" uniqKey="Koh W" first="Wui-Jin" last="Koh">Wui-Jin Koh</name><name sortKey="Nicandri, Katrina F" sort="Nicandri, Katrina F" uniqKey="Nicandri K" first="Katrina F." last="Nicandri">Katrina F. Nicandri</name><name sortKey="Sal Y Rosas, Victor G" sort="Sal Y Rosas, Victor G" uniqKey="Sal Y Rosas V" first="Victor G." last="Sal Y Rosas">Victor G. Sal Y Rosas</name><name sortKey="Seifert, Erin" sort="Seifert, Erin" uniqKey="Seifert E" first="Erin" last="Seifert">Erin Seifert</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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